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3-Cyanochromone
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3-Cyanochromone

CAS: 50743-17-4

Ref. 3D-FC54282

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Estimated delivery in United States, on Wednesday 8 Jan 2025

Product Information

Name:
3-Cyanochromone
Synonyms:
  • 4-Oxo-4H-1-benzopyran-3-carbonitrile
  • 4-oxo-4H-chromene-3-carbonitrile
Description:

3-Cyanochromone is an inhibitor of acetylcholinesterase (AChE) that belongs to the class of reversible covalent inhibitors. It has been shown to have a reversible inhibition constant of 2.5 to 4.5 μM for AChE in human serum and amine-binding sites in the active site of AChE. 3-Cyanochromone binds reversibly to the carbonyl group in the active methylene region, which is located near the amino acid tryptophan, thereby inhibiting the enzyme's activity by preventing its reaction with substrates. 3-Cyanochromone also inhibits butyrylcholinesterase (BChE), which is responsible for breaking down molecules of choline into acetylcholine, a neurotransmitter. This inhibition may lead to accumulation of acetylcholine and subsequent cholinergic crisis.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
171.15 g/mol
Formula:
C10H5NO2
Purity:
Min. 95%
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Hazard Info

UN Number:
EQ:
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H Statements:
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Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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