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n-(2-chloropyrimidin-4-yl)-n,2,3-trimethyl-2h-indazol-6-amine
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n-(2-chloropyrimidin-4-yl)-n,2,3-trimethyl-2h-indazol-6-amine

CAS: 444731-75-3

Ref. 3D-FC59031

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Estimated delivery in United States, on Wednesday 15 Jan 2025

Product Information

Name:
n-(2-chloropyrimidin-4-yl)-n,2,3-trimethyl-2h-indazol-6-amine
Synonyms:
  • 2H-Indazol-6-amine, N-(2-chloro-4-pyrimidinyl)-N,2,3-trimethyl-
  • N-(2-Chloropyrimidin-4-yl)-N-methyl-2,3-Methyl-2H-indazol-6-amine
  • N-(2-Chloropyrimidin-4-yl)-N-methyl-2,3-dimethyl-2H-indazol-6-amine
  • N-(2-chloro-4-pyrimidinyl)-N,2,3-trimethyl-2H-Indazol-6-amine
Description:

Pazopanib is an anti-cancer drug that belongs to the class of targeted therapies. It is used in the treatment of advanced renal cell carcinoma and soft tissue sarcoma. Pazopanib has been shown to inhibit angiogenesis, which may be due to its ability to inhibit the activation of endothelial cells and their migration. Pazopanib also inhibits tumor growth by interfering with cell cycle progression, which may be due to its ability to inhibit DNA synthesis or protein synthesis. The compound has been found to have a high number of genotoxic impurities, such as dimethyl sulfate and semiquantitative genotoxic impurities such as mutagenic impurities. These impurities can cause adverse effects on DNA, including mutations and chromosomal aberrations.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
287.75 g/mol
Formula:
C14H14N5Cl
Purity:
Min. 95%
MDL:
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HS code:

Hazard Info

UN Number:
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Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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