Cyclopentolate

CAS: 512-15-2

Ref. 3D-FC61687

Product Information

• Name: Cyclopentolate
• Synonyms: 2-Dimethylaminoethyl 2-(1-Hydroxycyclopentyl)-2-Phenyl-Acetate2-(1-Hydroxycyclopentyl)-2-Phenyl-Acetic Acid 2-Dimethylaminoethyl Es ter, 1-Hydroxy-α-phenylcyclopentaneacetic acid, 2-(dimethylamino)ethyl ester, 2-(Dimethylamino)Ethyl (1-Hydroxycyclopentyl)(Phenyl)Acetate, 2-(Dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate, 2-Dimethylaminoethyl 1-hydroxy-α-phenylcyclopentaneacetate, 2-Dimethylaminoethyl 2-(1-Hydroxycyclopentyl)-2-Phenylacetate, <span class="text-smallcaps">DL</span>-Cyclopentolate, Benzeneacetic acid, α-(1-hydroxycyclopentyl)-, 2-(dimethylamino)ethyl ester, Ciclopentolato, Cyclogyl, Cyclopentaneacetic acid, 1-hydroxy-α-phenyl-, 2-(dimethylamino)ethyl ester, Cyclopentoiate, Cyclopentolat, Cyclopentylate, DL-Cyclopentolate, Tsiklopentolat, β-Dimethylaminoethyl (1-hydroxycyclopentyl)phenylacetate
• CAS: 512-15-2

Description

Cyclopentolate is a muscarinic antagonist and is used as an ophthalmic drug to produce mydriasis. Cyclopentolate inhibits the metabolism of cyclopentyl-CoA via the 3-hydroxyacyl-CoA dehydrogenase, which leads to the accumulation of cyclopentyl-CoA in cells. This inhibition can cause metabolic disorders such as hyperlipidemia and diabetes mellitus, which are characterized by increased acid formation and reduced glucose uptake. Cyclopentolate also binds to DNA, inhibiting transcription, replication, and repair of DNA. The binding affinity of cyclopentolate to DNA is approximately 2500 times higher than that of other drugs in its class. Cyclopentolate has been shown to inhibit leukemia inhibitory factor (LIF) and the production of acid from fluorescein angiography

• Brand: Biosynth

Chemical properties

• Molecular weight: 291.39 g/mol
• Formula: C₁₇H₂₅NO₃
• Purity: Min. 95%
• Color/Form: White/Off-White Solid
• InChI: InChI=1S/C17H25NO3/c1-18(2)12-13-21-16(19)15(14-8-4-3-5-9-14)17(20)10-6-7-11-17/h3-5,8-9,15,20H,6-7,10-13H2,1-2H3
• InChI key: InChIKey=SKYSRIRYMSLOIN-UHFFFAOYSA-N
• SMILES: CN(C)CCOC(=O)C(c1ccccc1)C1(O)CCCC1