Cecropin B

CAS: 80451-05-4

Ref. 3D-FC73321

Product Information

• Name: Cecropin B
• Synonyms: H-Lys-Trp-Lys-Val-Phe-Lys-Lys-Ile-Glu-Lys-Met-Gly-Arg-Asn-Ile-Arg-Asn-Gly-Ile-Val-Lys-Ala-Gly-Pro-Ala-Ile-Ala-Val-Leu-Gly-Glu-Ala-Lys-Ala-Leu-NH2
• CAS: 80451-05-4

Description

Cecropin B is a peptide with antibacterial activity. It was originally isolated from the bee cecropia and has been shown to have potent in vitro antimicrobial activity against a broad range of bacterial strains, including methicillin-resistant Staphylococcus aureus (MRSA). Cecropin B is a hydrophobic peptide that binds to Toll-like receptor 4, which activates the transcriptional factor NF-κB. This leads to cell lysis by activating the protease cecropin A.
Cecropin B also has protective effects against autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. The peptide prevents the production of inflammatory cytokines by binding to Toll-like receptor 2 and Toll-like receptor 4. It also inhibits DNA synthesis by inhibiting polymerase chain reaction and protein synthesis by inhibiting ribosomal translocation.

• Brand: Biosynth

Chemical properties

• Molecular weight: 3,834.67 g/mol
• Formula: C₁₇₆H₃₀₂N₅₂O₄₁S
• Purity: Min. 95%