Curcurbitacin IIa

CAS: 60137-06-6

Ref. 3D-FC73839

Product Information

• Name: Curcurbitacin IIa
• Synonyms: (9β,10α,16α,24S)-16,24-Epoxy-2,25-dihydroxy-9-methyl-19-norlanosta-1,5-diene-3,11,22-trione, 19-Norlanosta-1,5-diene-3,11,22-trione, 16,24-epoxy-2,25-dihydroxy-9-methyl-, (9beta,10alpha,16alpha,24S)-, 19-Norlanosta-1,5-diene-3,11,22-trione, 16,24-epoxy-2,25-dihydroxy-9-methyl-, (9β,10α,16α,24S)-, Cucurbitacin S, Cucurbitacins, dihydrocucurbitacin F,25-0-acetate, hemsecin A
• CAS: 60137-06-6

Description

Curcurbitacin IIa is a cucurbitacin that has been shown to inhibit the growth of mouse tumor cells. It is also an anti-cancer compound and has been shown to suppress the proliferation of human T-cell lymphoma cells. Curcurbitacin IIa inhibits the activity of a variety of enzymes, including thymidine kinase, ribonucleotide reductase, DNA polymerase, and RNA polymerase. This compound also suppresses the production of prostaglandins by inhibiting cyclooxygenase. Curcurbitacin IIa has been found to bind specifically to calf thymus DNA in order to inhibit bacterial growth.

• Brand: Biosynth

Chemical properties

• Molecular weight: 498.65 g/mol
• Formula: C₃₀H₄₂O₆
• Purity: Min. 95%
• Color/Form: White/Off-White Solid