![4-[(4-Chloro-2-fluorophenyl)amino]-4-oxobutanoic acid](https://static.cymitquimica.com/products/3D/img/FC93725.png "Click to enlarge")
4-[(4-Chloro-2-fluorophenyl)amino]-4-oxobutanoic acid
CAS: 904810-52-2
Ref. 3D-FC93725
| 1g | Discontinued | ||
| 2g | Discontinued | ||
| 5g | Discontinued | ||
| 10g | Discontinued | ||
| 500mg | Discontinued |
Product Information
Name:
4-[(4-Chloro-2-fluorophenyl)amino]-4-oxobutanoic acid
Synonyms:
- Butanoic Acid, 4-[(4-Chloro-2-Fluorophenyl)Amino]-4-Oxo-
Description:
4-[(4-Chloro-2-fluorophenyl)amino]-4-oxobutanoic acid (4CFP) is a potent inhibitor of the enzyme acyl coenzyme A:cholesterol acyltransferase (ACAT). ACAT catalyzes the transfer of cholesterol from high density lipoprotein to low density lipoprotein. 4CFP has been shown to reduce cholesterol levels in animal models. The tautomeric forms of 4CFP are also active, and it has been shown that the sulfinyl form is more potent than the carbonyloxy form. The sulfinyl form is a competitive inhibitor of ACAT with respect to both substrates, whereas the carbonyloxy form is a noncompetitive inhibitor with respect to cholesterol.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
245.63 g/mol
Formula:
C10H9ClFNO3
Purity:
Min. 95%
InChI:
InChI=1S/C10H9ClFNO3/c11-6-1-2-8(7(12)5-6)13-9(14)3-4-10(15)16/h1-2,5H,3-4H2,(H,13,14)(H,15,16)
InChI key:
InChIKey=IAXPBKWZXXEWQX-UHFFFAOYSA-N
SMILES:
O=C(O)CCC(=O)Nc1ccc(Cl)cc1F
MDL:
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