1-[(4-Chlorophenyl)Methyl]-5-(Trifluoromethyl)Benzimidazol-2-Amine

CAS: 150493-34-8

Ref. 3D-FC98097

Product Information

• Name: 1-[(4-Chlorophenyl)Methyl]-5-(Trifluoromethyl)Benzimidazol-2-Amine
• Synonyms: Ns 638, 1-((4-Chlorophenyl)methyl)-5-(trifluoromethyl)-1H-benzimidazol-2-amine, 1H-Benzimidazol-2-amine, 1-((4-chlorophenyl)methyl)-5-(trifluoromethyl)-, 1-(4-chlorobenzyl)-5-(trifluoromethyl)-1H-benzimidazol-2-amine

Description

1-[(4-Chlorophenyl)Methyl]-5-(Trifluoromethyl)Benzimidazol-2-Amine is a molecule that has been shown to cause neuronal death in vitro and in vivo. It binds reversibly to the L-type voltage-gated calcium channels, which are important for neurotransmitter release and neuronal excitability. The blockade of these channels leads to an increase in intracellular calcium concentrations and subsequent neuronal death. 1-[(4-Chlorophenyl)Methyl]-5-(Trifluoromethyl)Benzimidazol-2-Amine has been shown to selectively inhibit granule cell death, while leaving other types of neurons unharmed. This drug can also be used as a blocker of glutamate receptors (NMDA).

• Brand: Biosynth

Chemical properties

• Molecular weight: 325.72 g/mol
• Formula: C₁₅H₁₁ClF₃N₃
• Purity: Min. 95%