alpha-(4-Chlorophenyl)-4-[(4-Fluorophenyl)Methyl]-1-Piperidineethanol

CAS: 119431-25-3

Ref. 3D-FC98752

Product Information

• Name: alpha-(4-Chlorophenyl)-4-[(4-Fluorophenyl)Methyl]-1-Piperidineethanol
• Synonyms: (+-)-alpha-(p-Chlorophenyl)-4-(p-fluorobenzyl)-1-piperidineethanol, 1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-ethanol, 1-(4-Chlorophenyl)-2-[4-(4-Fluorobenzyl)Piperidin-1-Yl]Ethanol, 1-(4-Chlorophenyl)-2-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]ethan-1-ol, 1-(4-Chlorophenyl)-2-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]ethanol, 1-Piperidineethanol, alpha-(4-chlorophenyl)-4-((4-fluorophenyl)methyl)-, (+-)-, 1-Piperidineethanol, alpha-(4-chlorophenyl)-4-(4-fluorophenyl)-, (+-)-, 1-Piperidineethanol, α-(4-chlorophenyl)-4-[(4-fluorophenyl)methyl]-, Eliprodil [INN], Sl 82-0715, Sl 820715, Unii-Yw62A6Tw29, α-(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol
• CAS: 119431-25-3

Description

Alpha-(4-chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol (CPFPE) is a neuronal death agent that inhibits the NMDA receptor and blocks the mitochondrial membrane potential. It has been shown to induce muscle spasms in mice, and it can be used as a model system for studying the effects of drugs on muscles. CPFPE has been shown to have side-effect profiles similar to those of ifenprodil, an antagonist of NMDA receptors. CPFPE has also been shown to bind to the NMDA receptor with high affinity and act as a competitive antagonist. This drug binds to the protein at its binding site, which is located on the outer surface of the receptor’s channel pore. The x-ray crystal structures show that CPFPE binds in such a way that it blocks access by glutamate and other amino acids into the channel pore, thereby blocking ion flow and preventing dep

• Brand: Biosynth

Chemical properties

• Molecular weight: 347.85 g/mol
• Formula: C₂₀H₂₃ClFNO
• Purity: Min. 95%