4,6-Dichloro-2-(methylthio)pyrimidine

CAS: 6299-25-8

Ref. 3D-FD09666

Product Information

• Name: 4,6-Dichloro-2-(methylthio)pyrimidine
• Synonyms: 2-Methylthio-4,6-dichloropyrimidine, 4,6-Dichloro-2-(methylmercapto)pyrimidine, 4,6-Dichloro-2-Methylpyrimidine-5-Thiol, 4,6-Dichloro-2-methylmercaptopyrimidine, 4,6-Dichloro-2-methylsulfanyl-pyrimidine, 4,6-Dichloropyrimidine Methyl Sulphide, NSC 44560, Pyrimidine, 4,6-dichloro-2-(methylthio)-, 4,6-Dichloro-2-Methylthio Pyrimidine, 4,6-dichloro-2-methylthio)pyrimidine

Description

4,6-Dichloro-2-(methylthio)pyrimidine is a compound that has an optical rotation of +8.5°. It has a melting point of 175° C and a boiling point of 264° C. The compound can be made via the Suzuki coupling reaction between methylamine and 2-chloropyrimidine. This reaction requires temperatures between -20° and 220°C, which can be achieved by recycling the steps in the reaction. 4,6-Dichloro-2-(methylthio)pyrimidine is soluble in organic solvents such as ethanol, but insoluble in water. This compound is found to have a molecular electrostatic potential of -0.59 eV, which is typical for primary amines. 4,6-Dichloro-2-(methylthio)pyrimidine has been shown to have antibiotic activity against bladder infection bacteria and crystal x-ray diffraction studies show that

• Brand: Biosynth

Chemical properties

• Molecular weight: 195.07 g/mol
• Formula: C₅H₄Cl₂N₂S
• Purity: Min. 95%
• InChI: InChI=1S/C5H4Cl2N2S/c1-10-5-8-3(6)2-4(7)9-5/h2H,1H3
• InChI key: InChIKey=FCMLONIWOAGZJX-UHFFFAOYSA-N
• SMILES: CSc1nc(Cl)cc(Cl)n1