![(2'R)-2'-Deoxy-6-O-ethyl-2'-fluoro-2'-methylguanosine cyclic 3',5'-[1-methylethyl (R)-phosphate]](https://static.cymitquimica.com/products/3D/img/FD102201.png "Click to enlarge")
(2'R)-2'-Deoxy-6-O-ethyl-2'-fluoro-2'-methylguanosine cyclic 3',5'-[1-methylethyl (R)-phosphate]
CAS: 1199809-32-9
Ref. 3D-FD102201
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Product Information
Sofosbuvir is a nucleotide analog that inhibits the hepatitis C virus (HCV) RNA-dependent RNA polymerase and prevents viral replication. Sofosbuvir is an inhibitor of HCV NS5B protein, which is essential for viral replication. Sofosbuvir has been shown to be effective against influenza A virus and picornaviruses in vitro, but not against other RNA viruses such as poliovirus and rhinovirus. It has also been shown to inhibit cancer cell growth in vitro and to inhibit the proliferation of replicating cells in culture. Sofosbuvir has been found to have good oral bioavailability, with a half-life of approximately 2 hours in humans, and can be taken with or without food.
Chemical properties
Technical inquiry about: 3D-FD102201 (2'R)-2'-Deoxy-6-O-ethyl-2'-fluoro-2'-methylguanosine cyclic 3',5'-[1-methylethyl (R)-phosphate]
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