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5-(2,2-Difluoroethenyl)-1-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Pyrimidine-2,4-Dione
CAS: 108711-80-4
Ref. 3D-FD102243
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Product Information
- 2'-Deoxy-5-(2,2-difluorovinyl)uridine
- 5-Dfv-DU
- Uridine, 2'-deoxy-5-(2,2-difluoroethenyl)-
- 2'-Deoxy-5-(2,2-Difluoroethenyl)Uridine
The inhibitory effect of 5-(2,2-difluoroethenyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione (AFX) on the proliferation of cells in culture was studied. AFX inhibited cell proliferation by inhibiting the kinase gene and reducing the rate of DNA synthesis. Acyclovir is a drug that is used to treat herpes simplex virus infections and other viral diseases such as chickenpox and shingles. It has been shown to be effective against a variety of viruses including HIV, influenza virus, hepatitis B virus, and herpes simplex virus type 1 (HSV-1). The mechanism of action for acyclovir is inhibition of viral DNA polymerase.
Chemical properties
Technical inquiry about: 3D-FD102243 5-(2,2-Difluoroethenyl)-1-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Pyrimidine-2,4-Dione
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