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4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid
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4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid

CAS: 17057-04-4

Ref. 3D-FD116589

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Estimated delivery in United States, on Friday 24 Jan 2025

Product Information

Name:
4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid
Synonyms:
  • 4-maleimidobenzoic acid
  • 4-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)benzoic acid
  • 4-(2,5-Dioxo-2,5-dihydropyrrol-1-yl)benzoic acid
  • 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoate
  • 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid
  • 4-Maleimidobenzoic acid
  • Benzoic acid, 4-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-
  • Benzoic acid, p-maleimido-
  • N-(4-Carboxyphenyl)maleimide
  • N-(p-Carboxyphenyl)maleimide
  • See more synonyms
  • NSC 14889
  • NSC 521355
  • p-(N-Maleimido)benzoic acid
  • p-Carboxyphenylmaleimide
  • p-Maleimidobenzoic acid
Description:

4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid is a monoclonal antibody that binds to the epidermal growth factor receptor (EGFR). It has been shown to be effective in treating glioma patients. 4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid binds to EGFR with an affinity greater than that of the natural ligand and blocks the binding of EGFR ligands such as epidermal growth factor (EGF), transforming growth factor alpha (TGFα), and platelet derived growth factor (PDGF). This prevents the activation of downstream signaling pathways that lead to cell proliferation, differentiation, and survival. The drug has also been shown to have a high viscosity at low concentrations.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
217.18 g/mol
Formula:
C11H7NO4
Purity:
Min. 95%
InChI:
InChI=1S/C11H7NO4/c13-9-5-6-10(14)12(9)8-3-1-7(2-4-8)11(15)16/h1-6H,(H,15,16)
InChI key:
InChIKey=LKUOJDGRNKVVFF-UHFFFAOYSA-N
SMILES:
O=C(O)c1ccc(N2C(=O)C=CC2=O)cc1
MDL:
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
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Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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