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4,6-Dimethyl-2-methylsulfonylpyrimidine
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4,6-Dimethyl-2-methylsulfonylpyrimidine

CAS: 35144-22-0

Ref. 3D-FD12082

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Estimated delivery in United States, on Wednesday 15 Jan 2025

Product Information

Name:
4,6-Dimethyl-2-methylsulfonylpyrimidine
Synonyms:
  • 2-(Methylsulfonyl)-4,6-dimethylpyrimidine
  • 2-Methanesulfonyl-4,6-Dimethyl-Pyrimidine
  • 2-Methanesulfonyl-4,6-dimethylpyrimidine
  • 4,6-Dimethyl-2-methylsulfonyl pyrimidine
  • Ambrisentan Intermediate-1
  • Pyrimidine, 4,6-dimethyl-2-(methylsulfonyl)-
Description:

4,6-Dimethyl-2-methylsulfonylpyrimidine (DMSP) is a chemical compound that is used as an intermediate in the synthesis of ambrisentan. DMSP can be prepared by reacting hydrochloric acid with 2-methylthioethanol and heating the mixture to about 160 °C. DMSP has been shown to bind to the endothelin-A receptor and may have antihypertensive properties. Validation studies have been carried out on DMSP using various chromatographic methods, including gas chromatography, high performance liquid chromatography, and thin layer chromatography. The results of these studies show that DMSP is a stable compound which does not react with oxygen or light when it is stored in an airtight container at room temperature for 12 months. DMSP also does not react with propionate, which makes it suitable for recycling.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
186.23 g/mol
Formula:
C7H10N2O2S
Purity:
Min. 95%
InChI:
InChI=1S/C7H10N2O2S/c1-5-4-6(2)9-7(8-5)12(3,10)11/h4H,1-3H3
InChI key:
InChIKey=ZHPSNGCLCHWTRG-UHFFFAOYSA-N
SMILES:
Cc1cc(C)nc(S(C)(=O)=O)n1
MDL:
Melting point:
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Density:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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