Product Information
- 1,8-Dinitropyrene [Nitroarenes]
- Brn 3413165
- Ccris 2585
- Pyrene, 1,8-dinitro-
1,8-Dinitropyrene is a genotoxic and mutagenic potential agent. It has been shown to induce nitric oxide synthase activity in rat liver microsomes, which may be due to its ability to activate the redox potential of the cells. 1,8-Dinitropyrene also induces enzyme activities such as p450 and nitroreductase in rat liver microsomes. This chemical has an analytical detection limit of 0.05 ppm and can be used as a marker for environmental exposure. 1,8-Dinitropyrene is genotoxic and carcinogenic in rats but not mice. It has been shown to induce mutations at the thymidine position of calf-thymus DNA and is potent inducer of genetic mutation in vitro.
Chemical properties
Technical inquiry about: 3D-FD146845 1,8-Dinitropyrene
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