(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutaneHydrochloride

CAS: 866783-13-3

Ref. 3D-FD150184

Product Information

• Name: (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutaneHydrochloride
• Synonyms: (1S)-4,5-Dimethoxy-1-(methylaminoethyl)benzocyclobutane HCl, (7S)-3,4-Dimethoxy-N-Methyl-Bicyclo[4,2,0]octa-1,3,5-triene-7-Methanamine HCl, (7S)-3,4-Dimethoxy-N-methylbicyclo[4.2.0]octa-1,3,5-triene-7-methanamine hydrochloride, (S)-N-[(4,5-Dimethoxybenzocyclobutan-1-yl)methyl]-N-methylamine hydrochloride, 1-[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]-N-methylmethanamine hydrochloride, 3,4-dimethoxy-N-methyl-bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine hydrochloride, Bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine, 3,4-dimethoxy-N-methyl-, hydrochloride (1:1), (7S)-, Bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine, 3,4-dimethoxy-N-methyl-, hydrochloride, (7S)-, Intermediate of IVA 1

Description

(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutaneHydrochloride is an intermediate for the synthesis of ivabradine. It is a white solid with a melting point of about 180 °C. The solvents used in this reaction are formamide and 1-bromo-3-chloropropane. The product is purified by recrystallization and then converted to ivabradine by hydrolysis of the acetal moiety using hydrochloric acid. (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutaneHydrochloride can be used as a pre-treatment to increase the efficiency of industrial processes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 243.73 g/mol
• Formula: C₁₂H₁₈ClNO₂
• Purity: Min. 95%