N1,N4-Di(buta-2,3-dienyl)butane-1,4-diamine
CAS: 93565-01-6
Ref. 3D-FD154279
| 25mg | 102.00 € | ||
| 50mg | 159.00 € | ||
| 100mg | 250.00 € | ||
| 250mg | 346.00 € | ||
| 500mg | 477.00 € |
Product Information
- 1,4-butanediamine, N~1~,N~4~-di-2,3-butadien-1-yl-
- N,N'-Di(buta-2,3-dien-1-yl)butane-1,4-diamine
N1,N4-Di(buta-2,3-dienyl)butane-1,4-diamine is a natural compound that inhibits polyamine oxidase (PAO), an enzyme that catalyzes the oxidation of polyamines. PAO is involved in the development of cancer and neuronal death. N1,N4-Di(buta-2,3-dienyl)butane-1,4-diamine has been shown to inhibit PAO activity in human carcinoma cell lines and to be neuroprotective in a rat model of Parkinson's disease. This agent also induces apoptosis by depolarizing mitochondrial membrane potential. It has been shown to be more potent than protocatechuic acid and irreversible inhibition can occur when cells are exposed for long periods of time.
Chemical properties
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