Desmethyl icaritin

CAS: 28610-31-3

Ref. 3D-FD15444

Product Information

• Name: Desmethyl icaritin
• Synonyms: 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one, 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)chromen-4-one, 4'-Desmethylicaritin, 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-, 4H-1-Benzopyran-4-one,3,5,7-trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)- (9CI), 8-C-Prenylkaempferol, 8-Prenylkaempferol, De-O-methylanhydroicaritin, Desmethylanhydroicaritin, Desmethylicaritin, Flavone, 3,4′,5,7-tetrahydroxy-8-(3-methyl-2-butenyl)-, Flavone,3,4',5,7-tetrahydroxy-8-(3-methyl-2-butenyl)- (8CI), Noranhydroicaritin
• CAS: 28610-31-3

Description

Icariin is a natural product that can be found in the plant genus Epimedium. Icariin has been shown to reduce body weight, fat mass, and cardiometabolic risk factors in pre-adipocyte 3T3-L1 cells by increasing the expression of c-jun and phosphorylation of signal pathways. Icariin also inhibits cell proliferation in human breast cancer cells MCF-7 by suppressing ERα expression and activating caspase-3. Icariin has also been shown to have protective effects on the heart and blood vessels by inhibiting platelet aggregation.

• Brand: Biosynth

Chemical properties

• Molecular weight: 354.35 g/mol
• Formula: C₂₀H₁₈O₆
• Purity: Min. 97 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C20H18O6/c1-10(2)3-8-13-14(22)9-15(23)16-17(24)18(25)19(26-20(13)16)11-4-6-12(21)7-5-11/h3-7,9,21-23,25H,8H2,1-2H3
• InChI key: InChIKey=NADCVNHITZNGJU-UHFFFAOYSA-N
• SMILES: CC(C)=CCc1c(O)cc(O)c2c(=O)c(O)c(-c3ccc(O)cc3)oc12