N-[1-(2,3-Dioleoyloxy)propyl]-n,n,n-trimethylammonium methyl-sulfate

CAS: 144189-73-1

Ref. 3D-FD157467

Product Information

• Name: N-[1-(2,3-Dioleoyloxy)propyl]-n,n,n-trimethylammonium methyl-sulfate
• Synonyms: 1-Propanaminium, N,N,N-trimethyl-2,3-bis[(1-oxo-9-octadecenyl)oxy]-, (Z,Z)-, methyl sulfate, 1-Propanaminium, N,N,N-trimethyl-2,3-bis[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]-, methyl sulfate (1:1), 1-Propanaminium, N,N,N-trimethyl-2,3-bis[[(9Z)-1-oxo-9-octadecenyl]oxy]-, methyl sulfate, DOTAP Me sulfate, DOTAP methosulfate, DOTAP methyl sulfate, N,N,N-trimethyl-2,3-bis[(9Z)-octadec-9-enoyloxy]propan-1-aminium methanesulfonate, N-(2,3-Dioleoyloxy-1-propyl)trimethylammonium methyl sulfate, N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium methyl sulfate

Description

Dioleoyloxypropyl-N,N,N-trimethylammonium methylsulfate (DOTAP) is an antibacterial agent that disrupts the bacterial membrane. It has been shown to inhibit the uptake of chlamydia by inhibiting the binding of chlamydia to cells and enhancing the detection of chlamydia in cells. DOTAP also has pharmacological properties that are related to its ability to interfere with cellular membranes. DOTAP can be used as a strategy for developing antibacterial agents because it inhibits bacterial growth by disrupting their cellular membranes. This results in a decrease in phosphatidylethanolamine levels, leading to increased cell death.

• Brand: Biosynth

Chemical properties

• Molecular weight: 758.19 g/mol
• Formula: C₄₃H₈₃NO₇S
• Purity: Min. 95%