1,25-Dihydroxyvitamin D3-26,23-lactone

CAS: 81203-50-1

Ref. 3D-FD171723

Product Information

• Name: 1,25-Dihydroxyvitamin D3-26,23-lactone
• Synonyms: (1S,3R,5Z,7E,23S,25R)-1,3,25-trihydroxy-23,26-epoxy-9,10-secocholesta-5,7,10-trien-26-one, (1alpha,3beta,5Z,7E,23S,25R)-1,3,23,25-Tetrahydroxy-9,10-secocholesta-5,7,10(19)-trien-26-oic gamma-lactone, (23S,25R)-1α,25-Dihydroxyvitamin D₃ 26,23-lactone, (3R,5S)-5-[(2R)-2-[(1R,3aS,4E,7aR)-4-[(2E)-2-[(3S,5R)-3,5-Dihydroxy-2-methylenecyclohexylidene]ethylidene]octahydro-7a-methyl-1H-inden-1-yl]propyl]dihydro-3-hydroxy-3-methyl-2(3H)-furanone, 1alpha,25-Dihydroxyvitamin D3-23,26-lactone, 2(3H)-Furanone, 5-[(2R)-2-[(1R,3aS,4E,7aR)-4-[(2E)-2-[(3S,5R)-3,5-dihydroxy-2-methylenecyclohexylidene]ethylidene]octahydro-7a-methyl-1H-inden-1-yl]propyl]dihydro-3-hydroxy-3-methyl-, (3R,5S)-, 9,10-Secocholesta-5,7,10(19)-trien-26-oic acid, 1,3,23,25-tetrahydroxy-, γ-lactone, (1α,3β,5Z,7E,23S,25R)-, Calcitriol lactone

Description

1,25-Dihydroxyvitamin D3-26,23-lactone is an analog of vitamin D3. It is a nucleophilic agent that can form covalent bonds with the side chain of amino acids in proteins. This analog has been shown to inhibit protein synthesis and induce apoptosis in prostate cancer cells by allylation and cleavage reactions. 1,25-Dihydroxyvitamin D3-26,23-lactone also inhibits cholesterol synthesis and collagen production. Thus, it may be used as a therapeutic agent for the treatment of prostate cancer.

• Brand: Biosynth

Chemical properties

• Molecular weight: 444.6 g/mol
• Formula: C₂₇H₄₀O₅
• Purity: 90%Min