Dimethyl Bromomalonate

CAS: 868-26-8

Ref. 3D-FD176438

Product Information

• Name: Dimethyl Bromomalonate
• Synonyms: 1,3-Dimethyl 2-bromopropanedioate, Dimethyl 2-bromomalonate, Dimethyl 2-bromopropanedioate, Dimethyl Bromopropanedioate, Dimethyl α-bromomalonate, Malonic acid, bromo-, dimethyl ester, NSC 175888, Propanedioic acid, 2-bromo-, 1,3-dimethyl ester, Propanedioic acid, bromo-, dimethyl ester
• CAS: 868-26-8

Description

Dimethyl bromomalonate is an organocatalytic reagent that converts alcohols to aldehydes and ketones, and is used in the synthesis of quinoline derivatives. It is also an effective antibacterial agent against Pseudomonas aeruginosa. The reaction mechanism involves conversion of malonic acid to methylmalonic acid by calcium carbonate, which reacts with a second molecule of malonic acid to form methylmalonyl dicarboxylic acid. This intermediate reacts with dimethyl bromomalonate to form the desired product and hydrogen chloride.

• Brand: Biosynth

Chemical properties

• Molecular weight: 211.01 g/mol
• Formula: C₅H₇BrO₄
• Purity: Min. 95%
• InChI: InChI=1S/C5H7BrO4/c1-9-4(7)3(6)5(8)10-2/h3H,1-2H3
• InChI key: InChIKey=NEMOJKROKMMQBQ-UHFFFAOYSA-N
• SMILES: COC(=O)C(Br)C(=O)OC