Dalfopristin

CAS: 112362-50-2

Ref. 3D-FD20779

Product Information

• Name: Dalfopristin
• Synonyms: (3R,4R,5E,10E,12E,14S,26R,26aS)-26-[[2-(Diethylamino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1- methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone(26R, (3R,4R,5E,10E,12E,14S,26R,26aS)-26-((2-(Diethylamino)ethyl)sulfonyl)-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-3-isopropyl-4,12-dimethyl-3H-21,18-nitrilo-1H,22H-pyrrolo(2,1-c)(1,8,4,19)dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone, (3R,4R,5E,10E,12E,14S,26R,26aS)-26-[[2-(Diethylamino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone, (3R,4R,5Z,10Z,12Z,14S,26R,26aS)-26-{[2-(diethylamino)ethyl]sulfonyl}-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-8,9,14,15,24,25,26,26a-octahydro-1H,3H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone, 3H-21,18-Nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine, virginiamycin M₁ deriv., 3H-21,18-Nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone, 26-[[2-(diethylamino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-, (3R,4R,5E,10E,12E,14S,26R,26aS)-, Dalfopristin [USAN:INN], Dalfopristina, Dalfopristina [INN-Spanish], Dalfopristine, Dalfopristine [INN-French], Dalfopristinum, Dalfopristinum [INN-Latin], Rp 54476, Unii-R9M4Fje48E, Virginiamycin M1, 26-((2-(diethylamino)ethyl)sulfonyl)-26,27-dihydro-, (26R,27S)-, Virginiamycin M₁, 26-[[2-(diethylamino)ethyl]sulfonyl]-26,27-dihydro-, (26R,27S)-
• CAS: 112362-50-2

Description

Dalfopristin is an antimicrobial agent that inhibits the growth of bacteria by blocking protein synthesis. It is a combination drug consisting of dalfopristin and quinupristin, which are active against Gram-positive bacteria but not against Gram-negative bacteria. The mechanism of action of dalfopristin is similar to erythromycin, but it has a broader spectrum of activity against resistant mutants. Dalfopristin has been used as a treatment for MRSA infections and in the prevention of postoperative infections after surgical procedures. Dalfopristin is also used in combination with other antibiotics for the treatment of various bacterial infections.

• Brand: Biosynth

Chemical properties

• Molecular weight: 690.85 g/mol
• Formula: C₃₄H₅₀N₄O₉S
• Purity: Min. 95%