Dapsone hydroxylamine

CAS: 32695-27-5

Ref. 3D-FD20799

Product Information

• Name: Dapsone hydroxylamine
• Synonyms: N-Hydroxy-4,4'-sulfonyldi(aniline)N-Hydroxy-4,4'-sulfonyldi-aniline4-[(4-Aminophenyl)sulfonyl]-N-hydroxy-benzenamine, 4-Amino-4'-hydroxylaminodiphenylsulfone, 4-Hydroxylamino-4'-aminophenyl sulfone, Dds-noh, Hads, N-Hydroxydapsone, Benzenamine, 4-((4-aminophenyl)sulfonyl)-N-hydroxy-, 4-[(4-aminophenyl)sulfonyl]-N-hydroxyaniline

Description

Dapsone hydroxylamine is a metabolite of dapsone. Dapsone hydroxylamine is a potent inhibitor of p-450 enzymes, which are involved in the metabolism of drugs and toxins. Dapsone hydroxylamine has been shown to have anti-oxidant effects, which could be due to its ability to inhibit the production of reactive oxygen species. It also has been shown to have an inhibitory effect on HIV infection in vitro by blocking the gp120 binding site on CD4 cells. In animal models, dapsone hydroxylamine has been shown to cause hemolysis in diabetic patients with erythrocyte acetylcholinesterase deficiency.

• Brand: Biosynth

Chemical properties

• Molecular weight: 264.3 g/mol
• Formula: C₁₂H₁₂N₂O₃S
• Purity: Min. 95%
• InChI: InChI=1S/C12H12N2O3S/c13-9-1-5-11(6-2-9)18(16,17)12-7-3-10(14-15)4-8-12/h1-8,14-15H,13H2
• InChI key: InChIKey=IYDSJDWESCGRKW-UHFFFAOYSA-N
• SMILES: Nc1ccc(S(=O)(=O)c2ccc(NO)cc2)cc1