Debromo hymenialdisine

CAS: 75593-17-8

Ref. 3D-FD20842

Product Information

• Name: Debromo hymenialdisine
• Synonyms: (4Z)-4-(2-Amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-4,5,6,7-tetrahydro-pyrrolo[2,3-c]azepin-8(1H)-one(Z)-2-Debromohymenialdisi ne(Z)-Debromohymenialdisine, pyrrolo[2,3-c]azepin-8(1H)-one, 4-(2-amino-3,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-4,5,6,7-tetrahydro-, (4Z)-

Description

Debromo hymenialdisine is a chemical inhibitor that binds to the epidermal growth factor receptor and blocks the activation of this receptor. It has been shown to have significant cytotoxicity against carcinoma cell lines, as well as mouse monoclonal antibody-activated inflammatory bowel disease. Debromo hymenialdisine also inhibits the production of proinflammatory cytokines such as IL-1ß, IL-6, and TNF-α. In addition, debromo hymenialdisine has been shown to be effective in inhibiting the growth of hepatocyte-like cells (HLCs) in solid tumours and in treating bowel disease in mice.

• Brand: Biosynth

Chemical properties

• Molecular weight: 245.24 g/mol
• Formula: C₁₁H₁₁N₅O₂
• Purity: Min. 95%
• InChI: InChI=1S/C11H11N5O2/c12-11-15-8(10(18)16-11)6-2-4-14-9(17)7-5(6)1-3-13-7/h1,3,13H,2,4H2,(H,14,17)(H3,12,15,16,18)/b8-6-
• InChI key: InChIKey=JYRJOQGKGMHTOO-VURMDHGXSA-N
• SMILES: NC1=N/C(=C2/CCNC(=O)c3[nH]ccc32)C(=O)N1