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2,5-Diamino-2,3-dihydrothiazolo[4,5-d]pyrimidine-7-(6H)-one
CAS: 22288-77-3
Ref. 3D-FD21449
| 1g | Discontinued | ||
| 2g | Discontinued | ||
| 5g | Discontinued |
Product Information
Name:
2,5-Diamino-2,3-dihydrothiazolo[4,5-d]pyrimidine-7-(6H)-one
Synonyms:
- 2,5-Diamino-thiazolo[4,5-d]pyrimidin-7(4H)-one
Description:
2,5-Diamino-2,3-dihydrothiazolo[4,5-d]pyrimidine-7-(6H)-one is an inhibitor of nucleoside phosphorylase. It has been shown to inhibit the growth of myeloid leukemia cells in culture. This drug may have a potential use in the treatment of T-cell leukemia and other malignancies involving purine metabolism. 2,5-Diamino-2,3-dihydrothiazolo[4,5-d]pyrimidine-7-(6H)-one is an analogue of 8-aminoguanine (8AG), which is a substrate for nucleoside phosphorylase. The enzyme converts 8AG into guanosine triphosphate (GTP) and purine nucleosides. The enzyme also converts purine nucleosides into their corresponding ribonucleotides. These ribonucleotides are
Notice:
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Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
183.19 g/mol
Formula:
C5H5N5OS
Purity:
Min. 95%
InChI:
InChI=1S/C5H5N5OS/c6-4-8-2-1(3(11)10-4)12-5(7)9-2/h(H5,6,7,8,9,10,11)
InChI key:
InChIKey=QWAUZOMMNINGON-UHFFFAOYSA-N
SMILES:
Nc1nc2nc(N)sc2c(=O)[nH]1
MDL:
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HS code:
