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2,5-Diamino-2,3-dihydrothiazolo[4,5-d]pyrimidine-7-(6H)-one
CAS: 22288-77-3
Ref. 3D-FD21449
| 1g | To inquire | |
| 2g | To inquire | |
| 5g | To inquire |
Product Information
- 2,5-Diamino-thiazolo[4,5-d]pyrimidin-7(4H)-one
2,5-Diamino-2,3-dihydrothiazolo[4,5-d]pyrimidine-7-(6H)-one is an inhibitor of nucleoside phosphorylase. It has been shown to inhibit the growth of myeloid leukemia cells in culture. This drug may have a potential use in the treatment of T-cell leukemia and other malignancies involving purine metabolism. 2,5-Diamino-2,3-dihydrothiazolo[4,5-d]pyrimidine-7-(6H)-one is an analogue of 8-aminoguanine (8AG), which is a substrate for nucleoside phosphorylase. The enzyme converts 8AG into guanosine triphosphate (GTP) and purine nucleosides. The enzyme also converts purine nucleosides into their corresponding ribonucleotides. These ribonucleotides are
Chemical properties
Technical inquiry about: 3D-FD21449 2,5-Diamino-2,3-dihydrothiazolo[4,5-d]pyrimidine-7-(6H)-one
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