Dibromobimane

CAS: 68654-25-1

Ref. 3D-FD21585

Product Information

• Name: Dibromobimane
• Synonyms: 3,5-Bis(bromomethyl)-2,6-dimethyl-1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dioneDBBRNSC 608550, 1,7-Bis(bromomethyl)-2,6-dimethylpyrazolo[1,2-a]pyrazole-3,5-dione, 1H,7H-Pyrazolo[1,2-a]pyrazole-1,7-dione, 3,5-bis(bromomethyl)-2,6-dimethyl-, 3,5-Bis(bromomethyl)-2,6-dimethyl-1H,7H-[1,2]diazolo[1,2-a]pyrazole-1,7-dione, 3,5-bis(bromomethyl)-2,6-dimethyl-1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dione, Dibromobimane (bBBr), NSC 608550, Thiolyte BB

Description

Dibromobimane is a chemical compound that has been used as a disinfectant and a water treatment agent. It is used to remove organic matter and bacteria from wastewater. Dibromobimane also binds to DNA, forming covalent bonds with sulfhydryl groups on proteins, which stabilizes the DNA molecule. This mechanism of action is particularly useful in treating autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus. Dibromobimane has also been shown to have reactive properties that may be due to its ability to form disulfide bonds with proteins or other molecules. The redox potential of dibromobimane can be manipulated by adding reductants, such as sodium borohydride or tetrathionate, which can allow it to be used for radiation therapy treatment trials.
Dibromobimane has been shown to inhibit ATP-binding cassette transporter (ABC) transporters in

• Brand: Biosynth

Chemical properties

• Molecular weight: 350.01 g/mol
• Formula: C₁₀H₁₀Br₂N₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C10H10Br2N2O2/c1-5-7(3-11)13-8(4-12)6(2)10(16)14(13)9(5)15/h3-4H2,1-2H3
• InChI key: InChIKey=OSIYFMVMZXJKSP-UHFFFAOYSA-N
• SMILES: Cc1c(CBr)n2c(CBr)c(C)c(=O)n2c1=O