1-(Dichloroacetyl)-1,2,3,4-Tetrahydroquinolin-6-Ol

CAS: 62265-67-2

Ref. 3D-FD21654

Product Information

• Name: 1-(Dichloroacetyl)-1,2,3,4-Tetrahydroquinolin-6-Ol
• Synonyms: 2,2-Dichloro-1-(6-Hydroxy-3,4-Dihydro-2H-Quinolin-1-Yl)Ethanone, 1-(Dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinol, 2,2-Dichloro-1-(3,4-dihydro-6-hydroxy-1(2H)-quinolinyl)ethanone, 6-Quinolinol, 1-(dichloroacetyl)-1,2,3,4-tetrahydro-, 2,2-Dichloro-1-(6-hydroxy-3,4-dihydro-2H-quinolin-1-yl)ethanone, 1-(Dichloroacetyl)-1,2,3,4-tetrahydroquinolin-6-ol, Ethanone, 2,2-dichloro-1-(3,4-dihydro-6-hydroxy-1(2H)-quinolinyl)-

Description

1-(Dichloroacetyl)-1,2,3,4-Tetrahydroquinolin-6-Ol is an antiamebic. It inhibits the growth of Entamoeba histolytica by inhibiting the phospholipase activity and the synthesis of cell wall lipids. This drug has been shown to be effective against infected hamsters in a hamster model. 1-(Dichloroacetyl)-1,2,3,4-Tetrahydroquinolin-6-Ol inhibits the growth of Entamoeba histolytica by binding to its phospholipase enzyme and preventing it from synthesizing cell wall lipids. The compound also binds to the esterase enzyme that breaks down fatty acids and glycerides in bacteria.

• Brand: Biosynth

Chemical properties

• Molecular weight: 260.12 g/mol
• Formula: C₁₁H₁₁Cl₂NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C11H11Cl2NO2/c12-10(13)11(16)14-5-1-2-7-6-8(15)3-4-9(7)14/h3-4,6,10,15H,1-2,5H2
• InChI key: InChIKey=OMZBOXOCCLZODD-UHFFFAOYSA-N
• SMILES: O=C(C(Cl)Cl)N1CCCc2cc(O)ccc21