9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid(RS-ofloxacin carboxylic acid)

CAS: 82419-35-0

Ref. 3D-FD21855

Product Information

• Name: 9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid(RS-ofloxacin carboxylic acid)
• Synonyms: 9,10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, (3R)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate, (3S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate, 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-, 9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9,10-Difluoro-3-Methyl-7-Oxo-2,3-Dihydro 7-H-Pyrido-1,2,3-DE]-1,4-Benzoxyazine-6-Carboxylic Acid, 9,10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, Difluorocarboylic Acid, Ofloxacin Q-Acid, Oxygen-fluorine acid

Description

Fluoroquinolones are a class of antibiotics that inhibit bacterial DNA replication by binding to the gyrase and topoisomerase IV enzymes. The carboxylic acid moiety is derived from levofloxacin, an antibiotic that is used for the treatment of acute bacterial sinusitis, pneumonia, and chronic bronchitis. The synthesis starts with the reaction of levofloxacin with triethylamine and sulfuric acid to form 9-fluoro-2,3-dihydro-7-hydroxy-3-methyl-7H-pyrido[1,2,3-de]-1,4-benzoxazine 6(5H)-carboxylic acid. This intermediate is then treated with chloroform and hydrochloric acid to produce 9,10-difluoro 2,3dihydro 3 methyl 7 oxo 7H pyrido[1,2,3 de

• Brand: Biosynth

Chemical properties

• Molecular weight: 281.21 g/mol
• Formula: C₁₃H₉F₂NO₄
• Purity: Min. 95%