Difluoromethylenediphosphonic acid

CAS: 10596-32-4

Ref. 3D-FD21876

Product Information

• Name: Difluoromethylenediphosphonic acid
• Synonyms: P,P'-(Difluoromethylene)bisphosphonic acidDifluoromethylene)bis[phosphonic acid](Difluoromethylene)bisphosphonic acid, (Difluoromethylene)bisphosphonic Acid, Difluoromethylene)bis[phosphonic Acid], Difluoromethylenediphosphonic Acid, P,P'-(Difluoromethylene)bisphosphonic Acid, Difluoromethlenediphosphonic Acid, (Difluoromethanediyl)Bis(Phosphonic Acid)
• CAS: 10596-32-4

Description

Difluoromethylenediphosphonic acid is a prodrug that is activated by the addition of fluoride ions. It inhibits tyrosine phosphatases, which are enzymes that catalyze the hydrolysis of phosphate groups from proteins. Difluoromethylenediphosphonic acid is also an analog of vitamin B1 and has been shown to inhibit insulin sensitivity in animals. Difluoromethylenediphosphonic acid can be used as a linker for peptide-based drugs and has optical properties that make it useful in biochemistry applications such as DNA sequencing, detection of single nucleotide polymorphisms (SNPs), and homology modeling.

• Brand: Biosynth

Chemical properties

• Molecular weight: 211.98 g/mol
• Formula: CH₄F₂O₆P₂
• Purity: Min. 95%
• InChI: InChI=1S/CH4F2O6P2/c2-1(3,10(4,5)6)11(7,8)9/h(H2,4,5,6)(H2,7,8,9)
• InChI key: InChIKey=HSRBLOWVRMGXEC-UHFFFAOYSA-N
• SMILES: O=P(O)(O)C(F)(F)P(=O)(O)O