N-(Diphenylmethylene)glycine methyl ester

CAS: 81167-39-7

Ref. 3D-FD22505

Product Information

• Name: N-(Diphenylmethylene)glycine methyl ester
• Synonyms: (Benzhydrylideneamino)acetic acid methyl esterBenzophenoneimine glycine methyl esterMethyl 3-aza-4,4-diphenylbut-3-enoate, DPM-Gly-OMe, Diphenylmethylene-Glycine Methyl ester, methyl N-(diphenylmethylidene)glycinate, (Benzhydrylideneamino)acetic Acid Methyl Ester
• CAS: 81167-39-7

Description

N-(Diphenylmethylene)glycine methyl ester is a product that is obtained by the reaction of glycine and an alkoxycarbonyl chloride. It is a hydrolysis product of N-phenylglyoxalic acid, an imine. The hydrolysis of N-(diphenylmethylene)glycine methyl ester yields glycine and formaldehyde. The alkali hydrolysis of N-(diphenylmethylene)glycine methyl ester yields glyoxalic acid and formaldehyde. This compound is used as a synthetic intermediate in the preparation of various drugs, such as 1-benzoyl-1-piperazine, 2-acetamidobenzoic acid, and 2-chloroethyl chloroformate. This compound can be prepared with high yield by reacting glycine with ethylene oxide followed by reaction with formaldehyde using a one pot process.

• Brand: Biosynth

Chemical properties

• Molecular weight: 253.3 g/mol
• Formula: C₁₆H₁₅NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C16H15NO2/c1-19-15(18)12-17-16(13-8-4-2-5-9-13)14-10-6-3-7-11-14/h2-11H,12H2,1H3
• InChI key: InChIKey=PQTOLHHWLUCKSB-UHFFFAOYSA-N
• SMILES: COC(=O)CN=C(c1ccccc1)c1ccccc1