Doxorubicinone
CAS: 24385-10-2
Ref. 3D-FD22607
| 1mg | 212.00 € | ||
| 2mg | 330.00 € | ||
| 5mg | 473.00 € | ||
| 10mg | 683.00 € | ||
| 25mg | 1,272.00 € |
Estimated delivery in United States, on Wednesday 29 May 2024
Product Information
Name:
Doxorubicinone
Synonyms:
- (8S,10S)-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
- (8S-cis)-7,8,9,10-Tetrahydro-6,8,10,11-tetrahydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
CAS:
Description:
Doxorubicinone is a prodrug that is metabolized to doxorubicin, which has a range of activities against tumour cells. It binds to the hydroxyl group on the enzyme topoisomerase II, preventing DNA unwinding and transcription. Doxorubicinone has been shown to have cardiac toxicity in experimental models and can cause cardiomyopathy in humans. The drug also reduces mitochondrial membrane potential and induces cell lysis.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
414.36 g/mol
Formula:
C21H18O9
Purity:
Min. 95 Area-%
Color/Form:
Red Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
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