rac N,O-Didesmethyl venlafaxine

CAS: 135308-74-6

Ref. 3D-FD24818

Product Information

• Name: rac N,O-Didesmethyl venlafaxine
• Synonyms: 4-[1-(1-Hydroxycyclohexyl)-2-(methylamino)ethyl]phenol, 4-[1-(1-Hydroxycyclohexyl)-2-(methylamino)ethyl]pheno, N,O-Didesmethylvenlafaxine, N,O-Didesvenlafaxine, Phenol, 4-[1-(1-hydroxycyclohexyl)-2-(methylamino)ethyl]-

Description

Rac N,O-Didesmethyl venlafaxine is a racemic mixture of the two enantiomers of venlafaxine. Rac N,O-Didesmethyl venlafaxine is used for the treatment of depression and other psychiatric disorders. Rac N,O-Didesmethyl venlafaxine is metabolized by glucuronidation to form the glucuronide conjugate, which is excreted in urine. Rac N,O-Didesmethyl venlafaxine has been shown to have a stereoselective effect on ventricular dysfunction in mice with heart failure. It also has a high affinity for opioid receptors and can cause drug interactions with other drugs that are opiate receptor agonists such as codeine or tramadol. Rac N,O-Didesmethyl venlafaxine also has an affinity for GABA receptors and can alter levels of neurotransmitters such as serotonin and dopamine.

• Brand: Biosynth

Chemical properties

• Molecular weight: 249.35 g/mol
• Formula: C₁₅H₂₃NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C15H23NO2/c1-16-11-14(12-5-7-13(17)8-6-12)15(18)9-3-2-4-10-15/h5-8,14,16-18H,2-4,9-11H2,1H3
• InChI key: InChIKey=MMSWXJSQCAEDLK-UHFFFAOYSA-N
• SMILES: CNCC(c1ccc(O)cc1)C1(O)CCCCC1