Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate

CAS: 632-93-9

Ref. 3D-FD29426

Product Information

• Name: Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate
• Synonyms: 3,5-Diethoxycarbonyl-1,4-dihydro-2,4,6-collidine, 1,4-Dihydro-2,4,6-trimethyl-3,5-dicarbethoxypyridine, 1,4-Dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylic acid diethyl ester, 1,4-Dihydro-3,5-dicarbethoxycollidine, 2,4,6-Trimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester, 2,4,6-Trimethyl-3,5-diethoxycarbonyl-1,4-dihydropyridine, 3,5-(Diethoxycarbonyl)-1,4-dihydrocollidine, 3,5-Bis(ethoxycarbonyl)-1,4-dihydro-2,4,6-trimethylpyridine, 3,5-Bis(ethoxycarbonyl)-1,4-dihydrocollidine, 3,5-Bis(ethoxycarbonyl)-2,4,6-trimethyl-1,4-dihydropyridine, 3,5-Dicarbethoxy-1,4-dihydro-2,4,6-trimethylpyridine, 3,5-Dicarbethoxy-1,4-dihydrocollidine, 3,5-Diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine, 3,5-Diethoxycarbonyl-1,4-dihydro-s-collidine, 3,5-Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate, 3,5-Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate, 3,5-Pyridinedicarboxylic Acid, 1,4-Dihydro-2,4,6-Trimethyl-, Diethyl Ester, 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,4,6-trimethyl-, 3,5-diethyl ester, DDC (porphyrinogen), Diethyl 1,4-Dihydro-2,4,6-Trimethyl-3,5-Pyridinedicarboxylate, Diethyl 1,4-dihydro-2,4,6-trimethylpyridine-3,5-dicarboxylate, Diethyl 2,4,6-tetramethyl-1,4-dihydropyridine-3,5-dicarboxylate, Diethyl 2,4,6-trimethyl-1,4-dihydro-3,5-pyridinedicarboxylate, Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate, Diethyl-1,4-dihydro-2,4,6-trimethyl-3,5-pyridine dicarboxylate, Diethyl-2,4,6-trimethyl-1,4-dihydropyridin-3,5-dicarboxylat, NSC 49528, NSC 8910
• CAS: 632-93-9

Description

Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate is a potent inhibitor of primary sclerosing cholangitis (PSC) and cellular transformation. It inhibits the production of proinflammatory cytokines by toll-like receptor 4 in vivo and the transcription of genes involved in hepatocyte growth. Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate also inhibits the synthesis of bile acids by inhibiting the synthesis of phosphatidylethanolamine and phosphatidylcholine. It has been shown to be effective in treating autoimmune diseases such as hepatic steatosis and liver cells that have been transformed into hepatocyte like cells. The drug also has inhibitory properties against body formation and cell lysis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 267.32 g/mol
• Formula: C₁₄H₂₁NO₄
• Purity: Min. 95%
• Color/Form: Yellow To Yellow Green Solid
• InChI: InChI=1S/C14H21NO4/c1-6-18-13(16)11-8(3)12(14(17)19-7-2)10(5)15-9(11)4/h8,15H,6-7H2,1-5H3
• InChI key: InChIKey=CDVAIHNNWWJFJW-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1C