2,4-Dichloro-α-(chloromethyl)benzyl alcohol

CAS: 13692-14-3

Ref. 3D-FD30620

Product Information

• Name: 2,4-Dichloro-α-(chloromethyl)benzyl alcohol
• Synonyms: (1R)-2-chloro-1-(2,4-dichlorophenyl)ethanol, (1S)-2-chloro-1-(2,4-dichlorophenyl)ethanol, 2,4-Dichloro-α-(chloromethyl)benzenemethanol, 2,4-Dichloro-α-chloromethylbenzenemethanol, 2-Chloro-1-(2,4-Dichlorophenyl)Ethanol, 2-Chloro-1-(2,4-dichlorophenyl)ethan-1-ol, Benzenemethanol, 2,4-dichloro-α-(chloromethyl)-, Benzyl alcohol, 2,4-dichloro-α-(chloromethyl)-, α-(2,4-Dichlorophenyl)-β-chloroethanol, α-(Chloromethyl)-2,4-dichlorobenzyl alcohol

Description

2,4-Dichloro-alpha-(chloromethyl)benzyl alcohol is an enantiopure compound that belongs to the class of acetylating agents. This drug is used in organic chemistry as a hydrophobic reagent to acetylate hydrophobic or electron-deficient carbon centers. It reacts with alcohols in the presence of aluminium and catalysts such as pyridine, 2,6-lutidine, or benzoyl chloride. The reaction time is dependent on the substrate binding and the kinetic effect. 2,4-Dichloro-alpha-(chloromethyl)benzyl alcohol has been shown to be an antifungal agent against Candida albicans. It has also been shown to be a chiral compound that can inhibit the growth of fungi by inhibiting the enzyme alcohol dehydrogenase which controls cellular levels of NADH2 and NAD+.

• Brand: Biosynth

Chemical properties

• Molecular weight: 225.5 g/mol
• Formula: C₈H₇Cl₃O
• Purity: Min. 95%
• Color/Form: Solid
• InChI: InChI=1S/C8H7Cl3O/c9-4-8(12)6-2-1-5(10)3-7(6)11/h1-3,8,12H,4H2
• InChI key: InChIKey=XHEPANNURIQWRM-UHFFFAOYSA-N
• SMILES: OC(CCl)c1ccc(Cl)cc1Cl