1,3-Di-o-tolylguanidine

CAS: 97-39-2

Ref. 3D-FD32800

Product Information

• Name: 1,3-Di-o-tolylguanidine
• Synonyms: Di-o-tolylguanidineDTG, 1,1-Bis(2-Methylphenyl)Guanidine, 1,2-Bis(2-methylphenyl)guanidine, 1,3-Bis(o-tolyl)guanidine, 1,3-Di(2-Tolyl)-Guanidin, 1,3-Di-(2-Tolyl)Guanidine, 1,3-Di-2-tolylguanidine, 1,3-Di-O-Tolyl-Guanidin, 1,3-Di-Orthotolyl-Guanidine, 1,3-Di-o-tolyguanidine, 1,3-Di-ortho-tolylguanidine, 1,3-Ditolylguanidine, 2,2'-Dimethyliminocarbanilide, Accelerator DOTG, Accelerator DT, AcceleratorDOTG, AcrochemDOTG, Akrochem DOTG, Cns 1001, DTG, Di-o-tolylguanidine, Diotolylguanidine, Ditolyguanidine, Ditolylguanidine,99%, Dotg, Eveite DOTG, Guanidine, 1,3-di-o-tolyl-, Guanidine, N,N′-bis(2-methylphenyl)-, N,N'-Di-Ortho-Tolylguanidine, N,N′-Bis(2-methylphenyl)guanidine, N,N′-Di-o-toluylguanidine, N,N′-Di-o-tolylguanidine, N-{(1E)-amino[(2-methylphenyl)amino]methylidene}-2-methylanilinium, NSC 132023, NSC 473, Nocceler DT, Rhenogran DOTG 70, Rubber Accelerator DOTG, Sanceler DT, Soxinol DT, Vanax Dotg, Vulcafor DOTG, Vulkacit DOTG

Description

1,3-Di-o-tolylguanidine (DTG) is a cytotoxic drug that interacts with cellular membranes. It is used to study the effects of drugs on cells and to identify the mechanism of action of drugs. DTG has been shown to cause neuronal death by interacting with a protein called synaptotagmin, which is involved in exocytosis. The drug binds to synaptotagmin and blocks its ability to bind to calcium ions, leading to calcium overload in the cell. This leads to an increase in intracellular calcium levels and causes neuronal death.

• Brand: Biosynth

Chemical properties

• Molecular weight: 239.32 g/mol
• Formula: C₁₅H₁₇N₃
• Purity: Min. 95%
• Color/Form: Powder