N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine
CAS: 139504-50-0
Ref. 3D-FD33453
| 10mg | 108.00 € | ||
| 25mg | 217.00 € | ||
| 50mg | 355.00 € | ||
| 100mg | 543.00 € | ||
| 250mg | 1,114.00 € |
Product Information
- Mertansine
- DM 1Maytansinoid DM 1
N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine is a thiol-containing derivative of maytansine. Maytansine and its derivatives kill cells by interfering with the formation of microtubules, and causing the depolymerisation of already formed microtubules. Antibody conjugates of N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine and the murine monoclonal antibody TA. 1, using linkers containing either a disulfide bond or a thioether bond, have been synthesised. These antibody conjugates bind to the HER-2/new oncogene protein that is expressed on human breast tumor cells.
Chemical properties
Technical inquiry about: 3D-FD33453 N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine
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