4,5-Dimethoxy-1-cyanobenzocyclobutane
CAS: 35202-54-1
Ref. 3D-FD34100
1g | Discontinued | ||
5g | Discontinued | ||
500mg | Discontinued |
Product Information
- 1,2-Dihydro-4,5-dimethoxybenzocyclobutene-1-carbonitrile
- 1-Cyano-4,5-dimethoxybenzocyclobutene
- 3,4-Dimethoxy-Bicyclo[4,2,0]octa-1,3,5-Triene-7-Carbonitrile
- 3,4-Dimethoxybicyclo[4.2.0]Octa-1,3,5-Triene-8-Carbonitrile
- 3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-triene-7-carbonitrile
- 4,5-Dimethoxy-1,2-Dihydrocyclobutabenzene-1-Carbonitrile
- 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile
- Bicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile, 3,4-dimethoxy-
- Intermediate of IVA 2
- NSC 154410
- See more synonyms
4,5-Dimethoxy-1-cyanobenzocyclobutane is an intermediate in the synthesis of ivabradine. It is produced by reacting 4,5-dimethoxybenzoic acid with cyanoacetic acid in the presence of acetonitrile and potassium carbonate in a refluxing solution. The reaction product crystallizes out from the solution. The chemical formula for 4,5-dimethoxy-1-cyanobenzocyclobutane is CHNO2. It can be synthesized using a variety of methods, including hydrogenation and dehydrogenation reactions. When heated to 300 degrees Celsius at atmospheric pressure, it undergoes cyclisation to produce ivabradine.