4,5-Dimethoxy-1-cyanobenzocyclobutane

CAS: 35202-54-1

Ref. 3D-FD34100

Product Information

• Name: 4,5-Dimethoxy-1-cyanobenzocyclobutane
• Synonyms: 1,2-Dihydro-4,5-dimethoxybenzocyclobutene-1-carbonitrile, 1-Cyano-4,5-dimethoxybenzocyclobutene, 3,4-Dimethoxy-Bicyclo[4,2,0]octa-1,3,5-Triene-7-Carbonitrile, 3,4-Dimethoxybicyclo[4.2.0]Octa-1,3,5-Triene-8-Carbonitrile, 3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-triene-7-carbonitrile, 4,5-Dimethoxy-1,2-Dihydrocyclobutabenzene-1-Carbonitrile, 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile, Bicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile, 3,4-dimethoxy-, Intermediate of IVA 2, NSC 154410, 3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile, 3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile

Description

4,5-Dimethoxy-1-cyanobenzocyclobutane is an intermediate in the synthesis of ivabradine. It is produced by reacting 4,5-dimethoxybenzoic acid with cyanoacetic acid in the presence of acetonitrile and potassium carbonate in a refluxing solution. The reaction product crystallizes out from the solution. The chemical formula for 4,5-dimethoxy-1-cyanobenzocyclobutane is CHNO2. It can be synthesized using a variety of methods, including hydrogenation and dehydrogenation reactions. When heated to 300 degrees Celsius at atmospheric pressure, it undergoes cyclisation to produce ivabradine.

• Brand: Biosynth

Chemical properties

• Molecular weight: 189.21 g/mol
• Formula: C₁₁H₁₁O₂N
• Purity: Min. 95%