Diphenyl selenide

CAS: 1132-39-4

Ref. 3D-FD34518

Product Information

• Name: Diphenyl selenide
• Synonyms: 1,1'-Selanyldibenzene, 1,1'-Selenobisbenzene, 1,1′-Selenobis[benzene], Benzene, 1,1'-selenobis-, Biphenyl selenide, Biphenyl selenium, Difenylselenium, Difenylselenium [Czech], Diphenyl selenium, Diphenylselane, Diphenylselenium, Nsc 49758, Phenyl selenide, Selenide, phenyl

Description

Diphenyl selenide is a chemical compound with the formula PhSe. It is a white solid that is soluble in organic solvents. The molecule consists of a central diphenyl group with two selenium atoms. It has been used as an anticancer agent, and is also known to inhibit cell proliferation by interfering with the production of DNA and RNA. Its mechanism of action involves its reaction with hypochlorous acid (HOCl) to form chloro-diphenyl-selenide (PhSeCl) which inhibits DNA synthesis. Diphenyl selenide can be synthesized by reacting diphenyl ether with sodium hydroxide, followed by hydrolysis of the resulting phenolate ester with dilute sulfuric acid.

Diphenyl selenide has been shown to exhibit anticancer properties when used in combination with other chemotherapeutic agents such as cisplatin and doxorubicin, and has been

• Brand: Biosynth

Chemical properties

• Molecular weight: 233.17 g/mol
• Formula: C₁₂H₁₀Se
• Purity: Min. 95%
• Color/Form: Clear Liquid
• InChI: InChI=1S/C12H10Se/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10H
• InChI key: InChIKey=ORQWTLCYLDRDHK-UHFFFAOYSA-N
• SMILES: c1ccc([Se]c2ccccc2)cc1