4-(Dimethylaminobenzylidene)rhodanine

CAS: 536-17-4

Ref. 3D-FD34805

Product Information

• Name: 4-(Dimethylaminobenzylidene)rhodanine
• Synonyms: (5E)-5-[4-(dimethylamino)benzylidene]-2-sulfanyl-1,3-thiazol-4(5H)-one, (5Z)-5-[4-(dimethylamino)benzylidene]-2-thioxo-1,3-thiazolidin-4-one, 4-Dimethylaminobenzalrhodanine, 4-Thiazolidinone, 5-[[4-(dimethylamino)phenyl]methylene]-2-thioxo-, 4′-(Dimethylamino)benzalrhodanine, 5-(4-(Dimethylamino)benzylidene)-2-thioxothiazolidin-4-one, 5-(4-Dimethylaminobenzaldehyde)rhodanine, 5-(p-Dimethylaminobenzylidene)rhodanine, 5-[4-(Dimethylamino)benzylidene]-2-thioxo-4-thiazolidone, 5-[[4-(Dimethylamino)phenyl]methylene]-2-thioxo-4-thiazolidinone, 5-[p-(Dimethylamino)benzylidene]rhodanine, 5-{[4-(Dimethylamino)Phenyl]Methylidene}-2-Thioxo-1,3-Thiazolidin-4-One, NSC 5042, Rhodanine, 5-[p-(dimethylamino)benzylidene]-, p-(Dimethylamino)benzal-5-rhodanine, p-(Dimethylamino)benzalrhodanine, p-(Dimethylamino)benzylidenerhodanine

Description

4-(Dimethylaminobenzylidene)rhodanine is a monosodium salt of the drug rhodanine. Rhodanine is a small-molecule, kinetically stable, and surface active agent that inhibits tumor growth by binding to sulfamoyl chloride, inhibiting the synthesis of DNA. Rhodanine has been shown to inhibit the growth of colon cancer cells in mice and human leukemia cells in vitro. This drug also inhibits the proliferation of erythrocytes and platelets. Rhodanine binds to chloride ions on cell surfaces and forms a complex with silver ions that can then be detected by electron microscopy or profiling studies using hydroxide solutions. The efficacy of 4-(dimethylaminobenzylidene)rhodanine as an anticancer agent is dependent on its concentration. A blood sample containing 4% dimethylaminobenzylidene rhodanine was found to have anti-t

• Brand: Biosynth

Chemical properties

• Molecular weight: 264.37 g/mol
• Formula: C₁₂H₁₂N₂OS₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C12H12N2OS2/c1-14(2)9-5-3-8(4-6-9)7-10-11(15)13-12(16)17-10/h3-7H,1-2H3,(H,13,15,16)/b10-7+
• InChI key: InChIKey=JJRVRELEASDUMY-JXMROGBWSA-N
• SMILES: CN(C)c1ccc(/C=C2/SC(=S)NC2=O)cc1