a-[4-[2-(Dimethylamino)ethoxy]phenyl]-b-ethyl-a-phenylphenethyl alcohol

CAS: 748-97-0

Ref. 3D-FD35460

Product Information

• Name: a-[4-[2-(Dimethylamino)ethoxy]phenyl]-b-ethyl-a-phenylphenethyl alcohol
• Synonyms: Tamoxifen Precursor, (±)-1,2-Diphenyl-1-[4-[2-(dimethylamino)ethoxy]phenyl]butan-1-ol, 1-Butanol, 1-[p-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenyl-, 1-{4-[2-(Dimethylamino)Ethoxy]Phenyl}-1,2-Diphenylbutan-1-Ol, Benzeneethanol, α-[4-[2-(dimethylamino)ethoxy]phenyl]-β-ethyl-α-phenyl-, alpha-(4-(2-(Dimethylamino)ethoxy)phenyl)-beta-ethyl-alpha-phenylphenethyl alcohol, α-[4-[2-(Dimethylamino)ethoxy]phenyl]-β-ethyl-α-phenylbenzeneethanol

Description

The isomeric form of a-[4-[2-(dimethylamino)ethoxy]phenyl]-b-ethyl-a-phenylphenethyl alcohol (DMPE) is used in the diagnosis of cancer. The DMPE molecule has two geometric isomers, cis and trans, that can be differentiated by spectrometric analysis. Cis-DMPE has been shown to bind to the estrogen receptor, blocking its activity. This compound also inhibits tumor growth in experimental models of breast cancer and prostate cancer. Trans-DMPE has shown some inhibitory effects against tumor growth as well. It binds to the estrogen receptor with high affinity, but does not block its activity like cis-DMPE does.

• Brand: Biosynth

Chemical properties

• Molecular weight: 389.53 g/mol
• Formula: C₂₆H₃₁NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C26H31NO2/c1-4-25(21-11-7-5-8-12-21)26(28,22-13-9-6-10-14-22)23-15-17-24(18-16-23)29-20-19-27(2)3/h5-18,25,28H,4,19-20H2,1-3H3
• InChI key: InChIKey=VFFBJZCCXOYRNN-UHFFFAOYSA-N
• SMILES: CCC(c1ccccc1)C(O)(c1ccccc1)c1ccc(OCCN(C)C)cc1