3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid

CAS: 55701-03-6

Ref. 3D-FD35498

Product Information

• Name: 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid
• Synonyms: (1R)-(+)-trans-Permethrinic acid, (1R)-trans-3-(2,2-Dichloro-1-ethenyl)-2,2-dimethylcyclopropanecarboxylic acid, (1R)-trans-3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid, (1R,3S)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid, (1S,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid, 1R-trans-Permethric acid, 3-(2,2-Dichloroethenyl)-2,2-Dimethylcyclo Propancarboxlix Acid, 3-(2,2-Dichloroethenyl)-2,2-Dimethylcyclopropanecarboxylic Acid, 3-(2,2-Dichloroethyenyl)-2,2-Dimethylcyclo Propanecarboxlic Acid, Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (1R,3S)-, Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (1R-trans)-
• CAS: 55701-03-6

Description

3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid (3DDC) is a synthetic metabolite of diclofenac that has been detected in the urine of humans and animals. It is an isomer of protocatechuic acid and has been shown to be a metabolite of diclofenac in humans. 3DDC can be detected in human maternal blood, urine, and plasma samples. Using liquid chromatography techniques, it has been found that 3DDC can be used as a marker for diclofenac exposure. 3DDC is also one of the metabolites of diclofenac that have been identified by monoclonal antibodies. It has been found to inhibit the activity of some enzymes involved in the production of prostaglandins, which are involved in inflammatory responses.

• Brand: Biosynth

Chemical properties

• Molecular weight: 209.07 g/mol
• Formula: C₈H₁₀Cl₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C8H10Cl2O2/c1-8(2)4(3-5(9)10)6(8)7(11)12/h3-4,6H,1-2H3,(H,11,12)
• InChI key: InChIKey=LLMLSUSAKZVFOA-UHFFFAOYSA-N
• SMILES: CC1(C)C(C=C(Cl)Cl)C1C(=O)O