3,4-Dihydro-1H-quinoxalin-2-one

CAS: 59564-59-9

Ref. 3D-FD42279

Product Information

• Name: 3,4-Dihydro-1H-quinoxalin-2-one
• Synonyms: 2(1H)-Quinoxalinone, 3,4-dihydro-, 2-Quinoxalinol, 3,4-Dihydro-, 3,4-Dihydroquinoxalin-2-ol, 3,4-dihydro-2(1H)-Quinoxalinone, 3,4-Dihydroquinoxalin-2(1H)-one

Description

3,4-Dihydro-1H-quinoxalin-2-one (DHQ) is a potent inhibitor of the enzyme dihydroorotase, which is involved in the conversion of DHEA to testosterone. The optimum reaction conditions for DHQ are magnetic resonance spectroscopy and a temperature of 60 degrees Celsius. It has been shown to have an effect on skeletal development and function in sciatic nerves. DHQ has also been shown to have anti-inflammatory effects in animal studies and may be used for the treatment of inflammatory diseases such as rheumatoid arthritis. It is also being investigated as a potential chemotherapeutic agent for leukemia cells that lack the enzyme 5' nucleotidase.

• Brand: Biosynth

Chemical properties

• Molecular weight: 148.16 g/mol
• Formula: C₈H₈N₂O
• Purity: Min. 95%
• InChI: InChI=1S/C8H8N2O/c11-8-5-9-6-3-1-2-4-7(6)10-8/h1-4,9H,5H2,(H,10,11)
• InChI key: InChIKey=HYTIPJFUWHYQON-UHFFFAOYSA-N
• SMILES: O=C1CNc2ccccc2N1