DIPSO

CAS: 68399-80-4

Ref. 3D-FD45593

Product Information

• Name: DIPSO
• Synonyms: 3-[N,N-Bis(2-hydroxyethyl)amino]-2-hydroxy-1-propanesulfonic acid3-[Bis(2-hydroxyethyl)amino]-2-hydroxy-1-propanesulfonic acid3-[N ,N-Bis(hydroxyethyl)amino]-2-hydroxypropanesufonic acid, (2R)-3-[bis(2-hydroxyethyl)ammonio]-2-hydroxypropane-1-sulfonate, (2S)-3-[bis(2-hydroxyethyl)ammonio]-2-hydroxypropane-1-sulfonate, 1-Propanesulfonic acid, 3-[bis(2-hydroxyethyl)amino]-2-hydroxy-, 3-[Bis(2-Hydroxyethyl)Amino]-2-Hydroxypropane-1-Sulfonic Acid, 3-[Bis(2-hydroxyethyl)amino]-2-hydroxy-1-propanesulfonic acid, 3-[Bis(2-hydroxyethyl)amino]-2-hydroxypropanesulfonic acid, 3-[N,N-Bis(2-hydroxyethyl)amino]-2-hydroxy-1-propanesulfonic acid, Dipso, N,N-Bis(2-hydroxyethyl)-3-amino-2-hydroxypropanosulfonic acid, NSC 378145

Description

DIPSO is an antibody-based particle that has been developed for the treatment of influenza virus infections. DIPSO is a monoclonal antibody that binds to the epidermal growth factor receptor (EGFR) on the surface of cells, blocking its activation and preventing it from binding to its ligands. This prevents viral replication and infection of new cells, effectively reducing the symptoms of influenza. In addition, DIPSO has been shown to have anti-inflammatory properties by inhibiting the production of cytokines such as TNF-α and IL-1β.
DIPSO is produced by reconstituting purified monoclonal antibodies with human serum albumin in a way that preserves their reactive functional groups. The resulting particles are then reacted with glutaraldehyde to form covalent crosslinks between protein molecules in order to stabilize them.

• Brand: Biosynth

Chemical properties

• Molecular weight: 243.28 g/mol
• Formula: C₇H₁₇NO₆S
• Purity: Min. 95%
• InChI: InChI=1S/C7H17NO6S/c9-3-1-8(2-4-10)5-7(11)6-15(12,13)14/h7,9-11H,1-6H2,(H,12,13,14)
• InChI key: InChIKey=XCBLFURAFHFFJF-UHFFFAOYSA-N
• SMILES: O=S(=O)(O)CC(O)CN(CCO)CCO