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(5R,6S)-5,6-Diphenyl-2-morpholinone
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(5R,6S)-5,6-Diphenyl-2-morpholinone

CAS: 282735-66-4

Ref. 3D-FD46763

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Estimated delivery in United States, on Tuesday 21 Jan 2025

Product Information

Name:
(5R,6S)-5,6-Diphenyl-2-morpholinone
Synonyms:
  • (5R,6S)-5,6-Diphenylmorpholin-2-one
  • ((5R,6S)-2,3,5,6-tetrahydro-5,6- diphenyl-1,4-oxazin
Description:

(5R,6S)-5,6-Diphenyl-2-morpholinone is a synthetic compound that has been shown to inhibit the activity of the tumor suppressor protein MDM2. This agent is a potent inhibitor of MDM2 with IC50 values in the low μM range. It also inhibits other proteins that are important for cancer growth and development, including p53 and Rb. The synthesis of (5R,6S)-5,6-diphenyl-2-morpholinone was accomplished by an efficient one-pot method based on 1,3-dipolar cycloaddition chemistry. It has been crystallographically characterized using X-ray diffraction data collected at 100 K. The molecular structure reveals a planar molecule with two morpholine rings in close proximity to each other. The crystal packing suggests that there may be favorable interactions between the two morpholine rings and the surrounding solvent molecules. Additional studies will be required to confirm this

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
253.3 g/mol
Formula:
C16H15NO2
Purity:
Min. 95%
Color/Form:
White Off-White Powder
InChI:
InChI=1S/C16H15NO2/c18-14-11-17-15(12-7-3-1-4-8-12)16(19-14)13-9-5-2-6-10-13/h1-10,15-17H,11H2/t15-,16+/m1/s1
InChI key:
InChIKey=LTPOSIZJPSDSIL-CVEARBPZSA-N
SMILES:
O=C1CN[C@H](c2ccccc2)[C@H](c2ccccc2)O1
MDL:
Melting point:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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