Diethyl (Trichloromethyl)phosphonate

CAS: 866-23-9

Ref. 3D-FD59860

Product Information

• Name: Diethyl (Trichloromethyl)phosphonate
• Synonyms: (Trichloromethyl)phosphonic Acid Diethyl Ester, 1-[Ethoxy(trichloromethyl)phosphoryl]oxyethane, Diethyl P-(trichloromethyl)phosphonate, Diethyl Trichloromethylphosphonate, Diethyl trichloromethanephosphonate, NSC 46567, Phosphonic acid, (trichloromethyl)-, diethyl ester, Phosphonic acid, P-(trichloromethyl)-, diethyl ester, Ro 3-0658
• CAS: 866-23-9

Description

Diethyl (trichloromethyl) phosphonate is an ethyl ester that reacts with epidermal growth factor at the phosphite group to produce a phosphonate. Diethyl (trichloromethyl) phosphonate can be prepared by reacting ethyl formate with phosphorus oxychloride in a hydrocarbon solvent. The resulting product is reacted with ethyl alcohol and then hydrolyzed to yield diethyl (trichloromethyl)phosphonate. This compound has shown promising activity as a topical agent for the treatment of epidermal growth and can be used in the preparation of other compounds, such as retinoic acid and chloride.

• Brand: Biosynth

Chemical properties

• Molecular weight: 255.46 g/mol
• Formula: C₅H₁₀Cl₃O₃P
• Purity: Min. 95%
• InChI: InChI=1S/C5H10Cl3O3P/c1-3-10-12(9,11-4-2)5(6,7)8/h3-4H2,1-2H3
• InChI key: InChIKey=RVAQSYWDOSHWGP-UHFFFAOYSA-N
• SMILES: CCOP(=O)(OCC)C(Cl)(Cl)Cl