Diethyl (1,3-Dithian-2-yl)phosphonate

CAS: 62999-73-9

Ref. 3D-FD59862

Product Information

• Name: Diethyl (1,3-Dithian-2-yl)phosphonate
• Synonyms: (1,3-Dithian-2-yl)phosphonic Acid Diethyl Ester
• CAS: 62999-73-9

Description

Diethyl (1,3-Dithian-2-yl)phosphonate is a podophyllotoxin analog that has been shown to have enhanced antitumor activity against murine leukemia and L1210 murine leukemia. It is an ancillary in the asymmetric synthesis of β-amino acid derivatives, benzylidene acetals, and podophyllotoxin analogues. The l1210 murine leukemia cells are sensitive to diethyl (1,3-dithian-2-yl)phosphonate because it can form covalent bonds with DNA by electron donation. These compounds are also found to be cytotoxic against other tumor cells including human breast cancer cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 256.32 g/mol
• Formula: C₈H₁₇O₃PS₂
• Purity: Min. 95%
• Color/Form: Solid
• InChI: InChI=1S/C8H17O3PS2/c1-3-10-12(9,11-4-2)8-13-6-5-7-14-8/h8H,3-7H2,1-2H3
• InChI key: InChIKey=BGXBJZCFBVTFFP-UHFFFAOYSA-N
• SMILES: CCOP(=O)(OCC)C1SCCCS1