4-(Difluoromethoxy)benzaldehyde

CAS: 73960-07-3

Ref. 3D-FD60084

Product Information

• Name: 4-(Difluoromethoxy)benzaldehyde
• Synonyms: Benzaldehyde, 4-(difluoromethoxy)-, Difluoromethyl 4-Formylphenyl ether, p-(Difluoromethoxy)benzaldehyde, p-Difluoromethoxybenzaldehyde

Description

4-(Difluoromethoxy)benzaldehyde is a hydroxy-substituted aromatic compound. It can be synthesized by the reaction of benzene with fluorine gas and difluoromethoxybenzene in the presence of aluminum chloride. The compound is a clear liquid with an odor reminiscent of bitter almond. It has been used as an industrial solvent and as a precursor in the synthesis of other chemicals. 4-(Difluoromethoxy)benzaldehyde can be converted to 2-fluoro-3-phenylpropionic acid by catalytic hydrogenation at room temperature, which is useful for the synthesis of phenylacetic acid derivatives. The compound has also been shown to have anti-inflammatory activities that are due to inhibition of cyclooxygenase and lipoxygenase enzymes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 172.13 g/mol
• Formula: C₈H₆F₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C8H6F2O2/c9-8(10)12-7-3-1-6(5-11)2-4-7/h1-5,8H
• InChI key: InChIKey=ZWCXOJYJJINQGU-UHFFFAOYSA-N
• SMILES: O=Cc1ccc(OC(F)F)cc1