S-[2-(Dimethylamino)ethyl]isothiourea Dihydrochloride

CAS: 16111-27-6

Ref. 3D-FD61318

Product Information

• Name: S-[2-(Dimethylamino)ethyl]isothiourea Dihydrochloride
• Synonyms: 2-(Dimethylamino)Ethyl Carbamimidothioate, 2-(Dimethylamino)Ethyl Carbamimidothioate Dihydrochloride, Carbamimidothioic acid, 2-(dimethylamino)ethyl ester, dihydrochloride, Carbamimidothioic acid, 2-(dimethylamino)ethyl ester, hydrochloride (1:2), Nordimaprit, Pseudourea, 2-[2-(dimethylamino)ethyl]-2-thio-, dihydrochloride, S-(2-Dimethylaminoethyl)isothiourea dihydrochloride, Skf 91487
• CAS: 16111-27-6

Description

S-[2-(Dimethylamino)ethyl]isothiourea Dihydrochloride is an inhibitor of tyrosinase, an enzyme that catalyzes the oxidation of tyrosine to dopa and dopaquinone. It binds to the active site of the enzyme and blocks its activity. S-[2-(Dimethylamino)ethyl]isothiourea Dihydrochloride has been shown to inhibit tyrosinase in animal experiments and in vitro studies, with a concentration-response curve that can be described by a Michaelis-Menten kinetic model. The inhibition of tyrosinase activity may be due to steric hindrance by the thiourea group or a covalent binding to amino acid residues on the protein surface. S-[2-(Dimethylamino)ethyl]isothiourea Dihydrochloride is also known as monomethyl auristatin E (MMAE

• Brand: Biosynth

Chemical properties

• Molecular weight: 220.16 g/mol
• Formula: C₅H₁₃N₃S·2HCl
• Purity: Min. 95%