2,3-Dichloro-5,8-dihydroxy-1,4-naphthalenedione

CAS: 14918-69-5

Ref. 3D-FD73273

Product Information

• Name: 2,3-Dichloro-5,8-dihydroxy-1,4-naphthalenedione
• Synonyms: 2,3-Dichloro-5,8-dihydroxy-1,4-naphthoquinone, 2,3-Dichloro-5,8-Dihydroxy-1,4-Naphtoquinone, Rarechem Ar Pa 0036, 2,3-Dichloro-5,8-Dihydroxy-1,4-Naphtoquinone 95+%, 2,3-Dichloro-5,8-Dihydroxy-1,4-Napthoquinone, 6,7-Dichloro-5,8-Dihydroxynaphthalene-1,4-Dione, 2,3-Dichloro-5,8-Dihydroxynaphthalene-1,4-Dione

Description

2,3-Dichloro-5,8-dihydroxy-1,4-naphthalenedione (DDD) is a chemical inhibitor of the proton response pathway. It is an analog of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). DDD has been shown to enhance the induction of apoptosis in human macrophages and leishmania parasites. This agent also inhibits the growth of some tumor cell lines and enhances the cytotoxicity of other chemotherapeutic drugs. DDD has low bioavailability due to its high lipophilicity and rapid metabolism by esterases and glucuronidases.

• Brand: Biosynth

Chemical properties

• Molecular weight: 259.04 g/mol
• Formula: C₁₀H₄Cl₂O₄
• Purity: Min. 95%
• Color/Form: Red Powder
• InChI: InChI=1S/C10H4Cl2O4/c11-7-8(12)10(16)6-4(14)2-1-3(13)5(6)9(7)15/h1-2,15-16H
• InChI key: InChIKey=KFAVXUQFBGHURZ-UHFFFAOYSA-N
• SMILES: O=C1C=CC(=O)c2c(O)c(Cl)c(Cl)c(O)c21