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Product Information
- Pyrido[3,2-d]pyrimidine, 2,4-dichloro-
2,4-Dichloropyrido[3,2-d]pyrimidine is a synthetic molecule that is structurally similar to donepezil. This compound inhibits the enzyme acetylcholinesterase (AChE), which breaks down the neurotransmitter acetylcholine. The 2,4-dichloropyrido[3,2-d]pyrimidine analogue has been shown to be a potent inhibitor of AChE and can be used to treat Alzheimer's disease and other neurodegenerative disorders. It may also be useful in treating Parkinson's disease. 2,4-Dichloropyrido[3,2-d]pyrimidine is a regioselective inhibitor of AChE with a chlorine atom at C5 position. It also has an electron donating group on the pyrimidinone ring at C6 position that stabilizes the transition state for hydrolysis by AChE and prevents
Chemical properties
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